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Issue 10, 2012
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Room temperature synthesis of isoquino[2,1-a][3,1]oxazine and isoquino[2,1-a]pyrimidine derivatives via visible light photoredox catalysis

Jun Xuan,a  Zhu-Jia Feng,a  Shu-Wen Duana  and  Wen-Jing Xiao*a 
Author affiliations

* Corresponding authors

a Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, China
E-mail: wxiao@mail.ccnu.edu.cn
Fax: +86 27 67862041
Tel: +86 27 67862041

Abstract

A novel and efficient construction of isoquino[2,1-a][3,1]oxazine and isoquino[2,1-a]pyrimidine frameworks has been realized by means of visible light photocatalytic reactions using air as the oxidant at room temperature. This strategy offers a direct and rapid access to two kinds of biologically important fused heterocycles in good to excellent yields.

Graphical abstract: Room temperature synthesis of isoquino[2,1-a][3,1]oxazine and isoquino[2,1-a]pyrimidine derivatives via visible light photoredox catalysis

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Publication details

The article was received on 05 Mar 2012, accepted on 12 Mar 2012 and first published on 13 Mar 2012


Article type: Communication
DOI: 10.1039/C2RA20403G
Citation: RSC Adv., 2012,2, 4065-4068
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    Room temperature synthesis of isoquino[2,1-a][3,1]oxazine and isoquino[2,1-a]pyrimidine derivatives via visible light photoredox catalysis

    J. Xuan, Z. Feng, S. Duan and W. Xiao, RSC Adv., 2012, 2, 4065
    DOI: 10.1039/C2RA20403G

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