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Issue 6, 2012
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A photocleavable affinity tag for the enrichment of alkyne-modified biomolecules

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Abstract

A new photocleavable affinity tag for use in the enrichment of alkyne-labelled biomolecules is reported. The tag is prepared via a concise synthetic route using readily available materials. The photolytic conditions employed for cleavage of the tag provide for a clean release of enriched biomolecules from streptavidin resin.

Graphical abstract: A photocleavable affinity tag for the enrichment of alkyne-modified biomolecules

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Publication details

The article was received on 13 Jan 2012, accepted on 17 Jan 2012 and first published on 18 Jan 2012


Article type: Communication
DOI: 10.1039/C2RA20082A
Citation: RSC Adv., 2012,2, 2244-2246
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    A photocleavable affinity tag for the enrichment of alkyne-modified biomolecules

    T. Koopmans, F. J. Dekker and N. I. Martin, RSC Adv., 2012, 2, 2244
    DOI: 10.1039/C2RA20082A

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