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M. V. Lomonosov Moscow State University of Fine Chemical Technology, 86 Vernadskiy ave., Moscow, Russian Federation
E-mail: mamaslov@mail.ru
; Fax: +7(495)9368901
; Tel: +7(495)9368901
b
Shemyakin-Ovchinnikov Institute of bioorganic chemistry RAS, 16/10 Ul. Miklukho-Maklaya, Moscow, Russian Federation
E-mail: chupin@nmr.ru
; Fax: +7(495)3355033
; Tel: +7(495)3352733
RSC Adv., 2012,2, 4600-4602
DOI:
10.1039/C2RA01356H
Received
25 Dec 2011,
Accepted
19 Mar 2012
First published online
20 Mar 2012
The synthesis of bivalent galactose-containing neutral lipids for the development of a targeted gene delivery system to the hepatocytes has been described. For introducing galactosyl ligands into the lipid molecule, a convenient approach based on modified Staudinger reaction was used.
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