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Issue 35, 2012
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A prototype continuous-flow liquid–liquid extraction system using open-source technology

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Abstract

A prototype continuous-flow liquid–liquid extraction system is reported. By harnessing several open-source software libraries, a computer control script was written using the Python programming language. Using a ‘computer-vision’ approach, this allowed the computer to monitor the interface level between the organic and aqueous phases using a simple webcam setup and (by dynamically controlling pump flow rate) to keep this interface within defined limits. The system enabled the efficient ‘inline’ extraction of excess reagent in hydrazone formations, dithiane formations and epoxidations. The initial results of dispersion measurement are also presented.

Graphical abstract: A prototype continuous-flow liquid–liquid extraction system using open-source technology

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Publication details

The article was received on 12 May 2012, accepted on 11 Jul 2012 and first published on 13 Jul 2012


Article type: Communication
DOI: 10.1039/C2OB25912E
Citation: Org. Biomol. Chem., 2012,10, 7031-7036
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    A prototype continuous-flow liquid–liquid extraction system using open-source technology

    M. O'Brien, P. Koos, D. L. Browne and S. V. Ley, Org. Biomol. Chem., 2012, 10, 7031
    DOI: 10.1039/C2OB25912E

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