Issue 3, 2012

The design and synthesis of novel IBiox N-heterocyclic carbeneligands derived from substituted amino-indanols

Abstract

A synthetic route towards a number of novel IBiox N-heterocyclic carbene (NHC) ligands has been developed. The resulting ligands have restricted flexibility and high steric demand. Preliminary studies have shown these ligands to give high levels of asymmetric induction in the copper-free allylic alkylation of cinnamyl bromide.

Graphical abstract: The design and synthesis of novel IBiox N-heterocyclic carbene ligands derived from substituted amino-indanols

Supplementary files

Article information

Article type
Communication
Submitted
22 Oct 2011
Accepted
14 Nov 2011
First published
16 Nov 2011

Org. Biomol. Chem., 2012,10, 512-515

The design and synthesis of novel IBiox N-heterocyclic carbene ligands derived from substituted amino-indanols

J. Levy, C. M. Latham, L. Roisin, N. Kandziora, P. D. Fruscia, A. J. P. White, S. Woodward and M. J. Fuchter, Org. Biomol. Chem., 2012, 10, 512 DOI: 10.1039/C1OB06780J

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