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Synthesis of 3,3-disubstituted oxindoles by one-pot integrated Brønsted base-catalyzed trichloroacetimidation of 3-hydroxyoxindoles and Brønsted acid-catalyzed nucleophilic substitution reaction

Cyril Piemontesi,a   Qian Wanga and   Jieping Zhu*a  
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a
Institute of Chemical Sciences and Engineering, École Polytechnique Fédérale de Lausanne, EPFL-SB-ISIC-LSPN, CH-1015 Lausanne, Switzerland
E-mail: jieping.zhu@epfl.ch;
Fax: (+41) 021 693 97 40 ;
Tel: (+41) 021 693 97 41
Org. Biomol. Chem., 2013,11, 1533-1536

DOI: 10.1039/C2OB27196F
Received 12 Nov 2012, Accepted 02 Jan 2013
First published online 03 Jan 2013
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