Au(III)-catalyzed intermolecular amidations of benzylic C–H bonds with sulfonamides and carboxamides are described. The protocol with the Au–bipy complex/N-bromosuccinimide system provides practical applications for synthesis of various amides via C–H activations. The reaction proceeds with high efficiency to give the corresponding amines, which are extremely useful synthetic intermediates.
Organic & Biomolecular Chemistry
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