without changing your settings we'll assume you are happy to receive all RSC cookies.
You can change your cookie settings by navigating to our Privacy and Cookies page and following the instructions. These instructions
are also obtainable from the privacy link at the bottom of any RSC page.
Department of Chemistry and Chemical Engineering, Gannan Normal University, Huanjin Campus, Ganzhou, Jiangxi 341000, P.R. China
; Fax: +86-797-8373670
; Tel: +86-797-8373670
Org. Biomol. Chem., 2012,10, 8814-8821
18 Jul 2012,
13 Sep 2012
First published online
18 Sep 2012
A simple, convenient and efficient metal-free catalyzed oxidative trimeric reaction of indoles toward a variety of 2-(1H-indol-3-yl)-2,3′-biindolin-3-one derivatives in moderate to excellent yields has been developed. This transformation proceeds via a tandem oxidative homocoupling reaction by using TEMPO in air as an environmentally benign oxidant. This methodology provides an alternative approach for the direct generation of all-carbon quaternary centers at the C3 position of indoles.