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Issue 38, 2012
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An alternative one-pot gold-catalyzed approach to the assembly of 11H-indolo[3,2-c]quinolines

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Abstract

A new one-pot approach was developed to construct the 11H-indolo[3,2-c]quinoline scaffold through a gold-catalysed reaction of 2-[(2-aminophenyl)ethynyl]phenylamine derivatives with aldehydes. The broad scope and the high regioselectivity of this new protocol as well as the mild and neutral reaction conditions make it a viable alternative to the previously reported procedures.

Graphical abstract: An alternative one-pot gold-catalyzed approach to the assembly of 11H-indolo[3,2-c]quinolines

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Publication details

The article was received on 17 Jul 2012, accepted on 09 Aug 2012 and first published on 10 Aug 2012


Article type: Paper
DOI: 10.1039/C2OB26380G
Citation: Org. Biomol. Chem., 2012,10, 7801-7808
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    An alternative one-pot gold-catalyzed approach to the assembly of 11H-indolo[3,2-c]quinolines

    G. Abbiati, A. Arcadi, M. Chiarini, F. Marinelli, E. Pietropaolo and E. Rossi, Org. Biomol. Chem., 2012, 10, 7801
    DOI: 10.1039/C2OB26380G

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