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Issue 37, 2012
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A ratiometric fluorescence sensor for caffeine

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Abstract

The dye disodium 3,4:3′,4′-bibenzo[b]thiophene-2,2′-disulfonate can be used as a molecular probe for the fluorimetric detection of caffeine in aqueous solution. The fluorescence response is attributed to non-covalent interactions of caffeine with the dye in the ground state and in the excited state. The bimodal interaction allows performing ratiometric measurements with very good selectivity over structurally related analytes. The dye was also used to develop a simple test strip for the visual differentiation of normal and decaffeinated coffee with a standard UV lamp.

Graphical abstract: A ratiometric fluorescence sensor for caffeine

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Publication details

The article was received on 11 Jun 2012, accepted on 23 Jul 2012 and first published on 09 Aug 2012


Article type: Paper
DOI: 10.1039/C2OB26117K
Citation: Org. Biomol. Chem., 2012,10, 7487-7490
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    A ratiometric fluorescence sensor for caffeine

    N. Luisier, A. Ruggi, S. N. Steinmann, L. Favre, N. Gaeng, C. Corminboeuf and K. Severin, Org. Biomol. Chem., 2012, 10, 7487
    DOI: 10.1039/C2OB26117K

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