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Paper

Potent enantioselective inhibition of DNA-dependent protein kinase (DNA-PK) by atropisomeric chromenone derivatives

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a
Newcastle Cancer Centre, Northern Institute for Cancer Research, School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, UK
E-mail: celine.cano@ncl.ac.uk ;
Tel: +44 (0) 1912227060
b
KuDOS Pharmaceuticals, Ltd, 410 Cambridge Science Park, Milton Road, Cambridge CB4 0PE, UK
c
AstraZeneca Oncology iMed, Mereside, Alderley Park, Macclesfield SK10 4TG, UK
Org. Biomol. Chem., 2012,10, 6747-6757

DOI: 10.1039/C2OB26035B
Received 29 May 2012, Accepted 12 Jul 2012
First published online 16 Jul 2012
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