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Issue 33, 2012
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A highly selective fluorescence sensor for Tin (Sn4+) and its application in imaging live cells

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Abstract

A naphthalimide–rhodamine B derivative was synthesized as a fluorescence turn-ON chemodosimeter for Sn4+. A colour change and marked enhancement of fluorescence was found in the presence of Sn4+, Cu2+ and Cr3+ due to the ring open reaction of rhodamine and a fluorescence resonance energy transfer process. Addition of the strong chelating agent ethylenediaminetetraacetic acid disodium salt (EDTA) partly released the cation from the complex with Sn4+ and restored the yellow fluorescence. In addition, the compound can be used as a fluorescent probe for Sn4+ in biological systems and may act as a tool with which to study the physiological functions of tin or pathogenesis in the human body.

Graphical abstract: A highly selective fluorescence sensor for Tin (Sn4+) and its application in imaging live cells

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Publication details

The article was received on 10 May 2012, accepted on 21 Jun 2012 and first published on 21 Jun 2012


Article type: Paper
DOI: 10.1039/C2OB25895A
Citation: Org. Biomol. Chem., 2012,10, 6740-6746
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    A highly selective fluorescence sensor for Tin (Sn4+) and its application in imaging live cells

    Q. Wang, C. Li, Y. Zou, H. Wang, T. Yi and C. Huang, Org. Biomol. Chem., 2012, 10, 6740
    DOI: 10.1039/C2OB25895A

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