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A practical entry to β-aryl-β-alkyl amino alcohols: application to the synthesis of a potent BACE1 inhibitor

Corresponding authors
Janssen Research and Development, Neuroscience Medicinal Chemistry Department, E-45007 Toledo, Spain
Fax: +34 925245771
Laboratorio de Moléculas Orgánicas, Centro de Investigación Príncipe Felipe, E-46012 Valencia, Spain
Departamento de Química Orgánica, Universidad de Valencia, E-46100 Burjassot, Spain
Fax: +34 963544939
Org. Biomol. Chem., 2012,10, 6758-6766

DOI: 10.1039/C2OB25845E
Received 03 May 2012, Accepted 21 Jun 2012
First published online 22 Jun 2012
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Organic & Biomolecular Chemistry - Information Point

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