A new triazole oxotechnetium chelating agent was synthesized via a ‘Click-to-Chelate’ strategy. In vivo evaluation of the corresponding 99mTc complex shows that the tracer exhibits very interesting properties for molecular imaging.
The international home of synthetic, physical and biomolecular organic chemistry.
Impact Factor
3.696
48 Issues per Year
Indexed in MEDLINE
Paper
Synthesis and biological evaluation of a new triazole–oxotechnetium complex
Show Affiliations
Hide Affiliations
*
Corresponding authors
a
CEA, iBiTecS, Service d'Ingénierie Moléculaire des Protéines, Laboratoire de Chimie du Vivant, bâtiment 152, 91191 Gif-sur-Yvette, France
E-mail: christophe.dugave@cea.fr ;
Fax: +33 16908 7991 ;
Tel: +33 16908 9938
E-mail: christophe.dugave@cea.fr ;
Fax: +33 16908 7991 ;
Tel: +33 16908 9938
Org. Biomol. Chem., 2012,10, 6484-6490
DOI: 10.1039/C2OB25774B
Received 23 Apr 2012, Accepted 13 Jun 2012
First published online 13 Jun 2012
Organic & Biomolecular Chemistry
- Information Point
Supplementary Info
-
Supplementary information
PDF (3508K)