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Ionization state of the catalytic dyad Asp25/25′ in the HIV-1 protease: NMR studies of site-specifically 13C labelled HIV-1 protease prepared by total chemical synthesis

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Institute for Biophysical Dynamics, Department of Chemistry, Department of Biochemistry and Molecular Biology, The University of Chicago, 929 East 57th Street, Chicago, USA
E-mail: skent@uchicago.edu ;
Tel: +1-773-702-4912
Org. Biomol. Chem., 2012,10, 5887-5891

DOI: 10.1039/C2OB25569C
Received 16 Mar 2012, Accepted 02 May 2012
First published online 01 Jun 2012

This article is part of themed collection: Organic & Biomolecular Chemistry 10th Anniversary
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