Jump to main content
Jump to site search

Issue 38, 2012
Previous Article Next Article

Lipase incorporated ionic liquid polymers as active, stable and reusable biocatalysts

Author affiliations

Abstract

The aim of this study was to develop ionic liquid (IL) polymer materials incorporating enzymes that can be used as active, stable and reusable biocatalysts. To this goal, Candida rugosa lipase has been microencapsulated in surfactant aggregates formed in an IL monomer or the solution of an IL monomer/IL and then incorporated into polymer frameworks through the free radical polymerization of an IL (1-vinyl-3-ethylimidazolium bis(trifluoromethyl-sulfonyl) amide) ([veim][Tf2N]). The activity, stability and reusability of such IL polymer materials containing lipase were evaluated using lipase-catalyzed hydrolysis of p-nitrophenyl butyrate (p-PNB) as a model reaction. Lipase encapsulated within ionic liquid polymer materials remained active and exhibited excellent stability in aqueous solutions. More importantly, these biopolymer materials retained most of their activity after five reaction cycles, in which biopolymers were recovered from the reaction mixture simply by centrifugation. This study promulgates a direction toward the design of IL – an interesting class of tunable and designable solvents – based polymer materials containing biomolecules via a combination of polymer and supramolecular chemistry for diverse applications.

Graphical abstract: Lipase incorporated ionic liquid polymers as active, stable and reusable biocatalysts

Back to tab navigation

Publication details

The article was received on 12 Mar 2012, accepted on 02 Aug 2012 and first published on 03 Aug 2012


Article type: Paper
DOI: 10.1039/C2OB25529D
Citation: Org. Biomol. Chem., 2012,10, 7707-7713
  •   Request permissions

    Lipase incorporated ionic liquid polymers as active, stable and reusable biocatalysts

    M. Moniruzzaman, K. Ino, N. Kamiya and M. Goto, Org. Biomol. Chem., 2012, 10, 7707
    DOI: 10.1039/C2OB25529D

Search articles by author

Spotlight

Advertisements