Issue 22, 2012

Diastereoselective synthesis of vicinal amino alcohols

Abstract

The vicinal amino alcohol is a common motif in natural products and pharmaceuticals. Amino acids constitute a natural, inexpensive, and enantiopure choice of starting material for the synthesis of such functionalities. However, the matters concerning diastereoselectivity are not obvious. This Perspective takes a look in the field of diastereoselective synthesis of vicinal amino alcohols starting from amino acids using various methods.

Graphical abstract: Diastereoselective synthesis of vicinal amino alcohols

Article information

Article type
Perspective
Submitted
20 Feb 2012
Accepted
28 Mar 2012
First published
29 Mar 2012

Org. Biomol. Chem., 2012,10, 4311-4326

Diastereoselective synthesis of vicinal amino alcohols

O. K. Karjalainen and A. M. P. Koskinen, Org. Biomol. Chem., 2012, 10, 4311 DOI: 10.1039/C2OB25357G

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