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Regioselective synthesis of pyrimido[1,2-a][1,3,5]triazin-6-ones via reaction of 1-(6-oxo-1,6-dihydropyrimidin-2-yl)guanidines with triethylorthoacetate: observation of an unexpected rearrangement

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a
Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
E-mail: phacwk@nus.edu.sg, nicks.sachdeva81@gmail.com;
Fax: +65 6779 1554 ;
Tel: +65 6516 2933
b
School of Pharmacy, Curtin Health Innovation Research Institute, Curtin University of Technology, GPO Box 1987, Perth, Western Australia 6845, Australia
Org. Biomol. Chem., 2012,10, 4586-4596

DOI: 10.1039/C2OB25195G
Received 26 Jan 2012, Accepted 03 Apr 2012
First published online 03 Apr 2012
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