In the presence of p-toluenesulfonic acid and iodine, styrene derivatives undergo head-to-tail dimerization followed by trapping with nitriles to yield the corresponding Ritter-type products.
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Iodine mediated/Brønsted acid-catalyzed dimerization of vinylarenes: a tandem reaction through Ritter trapping to produce N-(4-iodo-1,3-diarylbutyl) acetamides
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a
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, P.R. China
E-mail: chehjm@scut.edu.cn ;
Fax: (+86) 20-87110622 ;
Tel: +86 020 8711 0695
E-mail: chehjm@scut.edu.cn ;
Fax: (+86) 20-87110622 ;
Tel: +86 020 8711 0695
b
Experiment and Practice Training Center, GuangDong Food and Drug Vocational College, Guangzhou, P.R. China
Org. Biomol. Chem., 2012,10, 3610-3612
DOI: 10.1039/C2OB25142F
Received 18 Jan 2012, Accepted 15 Mar 2012
First published online 03 Apr 2012
Organic & Biomolecular Chemistry
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