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Issue 18, 2012
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Iodine mediated/Brønsted acid-catalyzed dimerization of vinylarenes: a tandem reaction through Ritter trapping to produce N-(4-iodo-1,3-diarylbutyl) acetamides

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Abstract

In the presence of p-toluenesulfonic acid and iodine, styrene derivatives undergo head-to-tail dimerization followed by trapping with nitriles to yield the corresponding Ritter-type products.

Graphical abstract: Iodine mediated/Brønsted acid-catalyzed dimerization of vinylarenes: a tandem reaction through Ritter trapping to produce N-(4-iodo-1,3-diarylbutyl) acetamides

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Publication details

The article was received on 18 Jan 2012, accepted on 15 Mar 2012 and first published on 03 Apr 2012


Article type: Communication
DOI: 10.1039/C2OB25142F
Citation: Org. Biomol. Chem., 2012,10, 3610-3612
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    Iodine mediated/Brønsted acid-catalyzed dimerization of vinylarenes: a tandem reaction through Ritter trapping to produce N-(4-iodo-1,3-diarylbutyl) acetamides

    J. Huang, Z. Ye, D. Chen and H. Zhu, Org. Biomol. Chem., 2012, 10, 3610
    DOI: 10.1039/C2OB25142F

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