Issue 18, 2012

Iodine mediated/Brønsted acid-catalyzed dimerization of vinylarenes: a tandem reaction through Ritter trapping to produce N-(4-iodo-1,3-diarylbutyl) acetamides

Abstract

In the presence of p-toluenesulfonic acid and iodine, styrene derivatives undergo head-to-tail dimerization followed by trapping with nitriles to yield the corresponding Ritter-type products.

Graphical abstract: Iodine mediated/Brønsted acid-catalyzed dimerization of vinylarenes: a tandem reaction through Ritter trapping to produce N-(4-iodo-1,3-diarylbutyl) acetamides

Supplementary files

Article information

Article type
Communication
Submitted
18 Jan 2012
Accepted
15 Mar 2012
First published
03 Apr 2012

Org. Biomol. Chem., 2012,10, 3610-3612

Iodine mediated/Brønsted acid-catalyzed dimerization of vinylarenes: a tandem reaction through Ritter trapping to produce N-(4-iodo-1,3-diarylbutyl) acetamides

J. Huang, Z. Ye, D. Chen and H. Zhu, Org. Biomol. Chem., 2012, 10, 3610 DOI: 10.1039/C2OB25142F

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