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Chemoselective cyclization of unprotected linear peptides by α-ketoacid–hydroxylamine amide-ligation

Takeo Fukuzumi,a   Lei Jua and   Jeffrey W. Bode*b  
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Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, USA
Laboratorium für Organische Chemie, ETH-Zürich, HCl F-315 Wolfgang Pauli Strasse 10, Zürich, Switzerland
Org. Biomol. Chem., 2012,10, 5837-5844

DOI: 10.1039/C2OB25129A
Received 17 Jan 2012, Accepted 21 Feb 2012
First published online 22 Feb 2012

This article is part of themed collection: Organic & Biomolecular Chemistry 10th Anniversary
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