Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 30, 2012
Previous Article Next Article

Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4)

Author affiliations

Abstract

The development of novel peptide and peptidomimetic ligands for the CXC chemokine receptor 4 (CXCR4) as therapeutic agents for HIV-1 infection, cancer, and immune system diseases has grown over the last decade. In this perspective article, the design of CXCR4 agonists and antagonists from endogenous stromal cell-derived factor-1 (SDF-1)/CXCL12 and horseshoe crab-derived antimicrobial peptides and their therapeutic and diagnostic applications are described.

Graphical abstract: Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4)

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 14 Jan 2012, accepted on 16 Mar 2012 and first published on 19 Mar 2012


Article type: Perspective
DOI: 10.1039/C2OB25107H
Citation: Org. Biomol. Chem., 2012,10, 5720-5731
  •   Request permissions

    Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4)

    S. Oishi and N. Fujii, Org. Biomol. Chem., 2012, 10, 5720
    DOI: 10.1039/C2OB25107H

Search articles by author