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Issue 16, 2012
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Dynamic photo-control of kinesin on a photoisomerizable monolayer – hydrolysis rate of ATP and motility of microtubules depending on the terminal group

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Abstract

The reversibly and repeatedly altered gliding motility of microtubules driven by kinesin on the photoresponsive monolayer surface is studied. It was confirmed that an azobenzene monolayer surface needs to have free amino terminal groups for the successful dynamic control of the motility of microtubule. The surface of the azobenzene monolayer with terminal amino groups can dynamically control the ATP hydrolysis activity of kinesin which resulted in the change in motility of the microtubules.

Graphical abstract: Dynamic photo-control of kinesin on a photoisomerizable monolayer – hydrolysis rate of ATP and motility of microtubules depending on the terminal group

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Publication details

The article was received on 23 Dec 2011, accepted on 19 Feb 2012 and first published on 21 Feb 2012


Article type: Paper
DOI: 10.1039/C2OB07167C
Citation: Org. Biomol. Chem., 2012,10, 3321-3331
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    Dynamic photo-control of kinesin on a photoisomerizable monolayer – hydrolysis rate of ATP and motility of microtubules depending on the terminal group

    M. K. A. Rahim, T. Kamei and N. Tamaoki, Org. Biomol. Chem., 2012, 10, 3321
    DOI: 10.1039/C2OB07167C

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