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Issue 20, 2012
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Biomedical nanomaterials for imaging-guided cancer therapy

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Abstract

To date, even though various kinds of nanomaterials have been evaluated over the years in order to develop effective cancer therapy, there is still significant challenges in the improvement of the capabilities of nano-carriers. Developing a new theranostic nanomedicine platform for imaging-guided, visualized cancer therapy is currently a promising way to enhance therapeutic efficiency and reduce side effects. Firstly, conventional imaging technologies are reviewed with their advantages and disadvantages, respectively. Then, advanced biomedical materials for multimodal imaging are illustrated in detail, including representative examples for various dual-modalities and triple-modalities. Besides conventional cancer treatment (chemotherapy, radiotherapy), current biomaterials are also summarized for novel cancer therapy based on hyperthermia, photothermal, photodynamic effects, and clinical imaging-guided surgery. In conclusion, biomedical materials for imaging-guided therapy are becoming one of the mainstream treatments for cancer in the future. It is hoped that this review might provide new impetus to understand nanotechnology and nanomaterials employed for imaging-guided cancer therapy.

Graphical abstract: Biomedical nanomaterials for imaging-guided cancer therapy

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Publication details

The article was received on 04 Jul 2012, accepted on 07 Aug 2012 and first published on 09 Aug 2012


Article type: Review Article
DOI: 10.1039/C2NR31715J
Citation: Nanoscale, 2012,4, 6135-6149
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    Biomedical nanomaterials for imaging-guided cancer therapy

    Y. Huang, S. He, W. Cao, K. Cai and X. Liang, Nanoscale, 2012, 4, 6135
    DOI: 10.1039/C2NR31715J

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