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Issue 2, 2012
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Gellan gum capped silver nanoparticle dispersions and hydrogels: cytotoxicity and in vitro diffusion studies

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Abstract

The preparation of highly stable water dispersions of silver nanoparticles using the naturally available gellan gum as a reducing and capping agent is reported. Further, exploiting the gel formation characteristic of gellan gum silver nanoparticle incorporated gels have also been prepared. The optical properties, morphology, zeta potential and long-term stability of the synthesized silver nanoparticles were investigated. The superior stability of the gellan gum–silver nanoparticle dispersions against pH variation and electrolyte addition is revealed. Finally, we studied the cytotoxicity of AgNP dispersions in mouse embryonic fibroblast cells (NIH3T3) and also evaluated the in vitro diffusion of AgNP dispersions/gels across rat skin.

Graphical abstract: Gellan gum capped silver nanoparticle dispersions and hydrogels: cytotoxicity and in vitro diffusion studies

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Publication details

The article was received on 28 Jul 2011, accepted on 17 Oct 2011 and first published on 01 Dec 2011


Article type: Paper
DOI: 10.1039/C1NR10957J
Citation: Nanoscale, 2012,4, 563-567
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    Gellan gum capped silver nanoparticle dispersions and hydrogels: cytotoxicity and in vitro diffusion studies

    S. Dhar, P. Murawala, A. Shiras, V. Pokharkar and B. L. V. Prasad, Nanoscale, 2012, 4, 563
    DOI: 10.1039/C1NR10957J

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