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Issue 12, 2012
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Ursane-type pentacyclic triterpenoids as useful platforms to discover anticancer drugs

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Abstract

Covering: up to December 2011

This review highlights the potential of natural and semisynthetic ursane-type triterpenoids as candidates for the design of multi-target bioactive compounds, with focus on their anticancer effects. A brief illustration of the biosynthesis, sources, and general biological effects of the main classes of naturally occurring pentacyclic triterpenoids (PTs) are provided.

Graphical abstract: Ursane-type pentacyclic triterpenoids as useful platforms to discover anticancer drugs

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Publication details

The article was received on 04 May 2012 and first published on 09 Oct 2012


Article type: Review Article
DOI: 10.1039/C2NP20060K
Citation: Nat. Prod. Rep., 2012,29, 1463-1479
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    Ursane-type pentacyclic triterpenoids as useful platforms to discover anticancer drugs

    J. A. R. Salvador, V. M. Moreira, B. M. F. Gonçalves, A. S. Leal and Y. Jing, Nat. Prod. Rep., 2012, 29, 1463
    DOI: 10.1039/C2NP20060K

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