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Issue 2, 2012
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The biodistribution of maltotriose modified poly(propylene imine) (PPI) dendrimers conjugated with fluorescein—proofs of crossing blood–brain–barrier

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Abstract

Oligosaccharide-modified poly(propylene imine) dendrimers are promising candidates as drug carriers and as anti-prion agents. Here, we report the biodistribution of maltotriose-modified 4th generation poly(propylene imine) (PPI) dendrimers and their ability to cross the blood–brain–barrier that is important if these glycodendrimers are considered as potential therapeutic agents in the central nervous system (CNS).

Graphical abstract: The biodistribution of maltotriose modified poly(propylene imine) (PPI) dendrimers conjugated with fluorescein—proofs of crossing blood–brain–barrier

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Publication details

The article was received on 26 May 2011, accepted on 01 Aug 2011 and first published on 22 Aug 2011


Article type: Letter
DOI: 10.1039/C1NJ20444K
Citation: New J. Chem., 2012,36, 350-353
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    The biodistribution of maltotriose modified poly(propylene imine) (PPI) dendrimers conjugated with fluorescein—proofs of crossing blood–brain–barrier

    A. Janaszewska, B. Ziemba, K. Ciepluch, D. Appelhans, B. Voit, B. Klajnert and M. Bryszewska, New J. Chem., 2012, 36, 350
    DOI: 10.1039/C1NJ20444K

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