Selective and competitive cysteine chemosensing: resettable fluorescent “turn on” aqueous detection via Cu2+ displacement and salicylaldimine hydrolysis

Abstract

A novel rechargeable meso-aryl Bodipy-based Cys sensing ensemble has been developed (“turn on,” Φ_F = <0.05 → 0.72, limit of detection = 6.0 × 10⁻⁶ M) with exceptional selectivity over homocysteine, N-acetylcysteine, glutathione (GSH) and methionine.