Jump to main content
Jump to site search

Issue 6, 2012
Previous Article Next Article

Facile and large-scale synthesis of Gd(OH)3 nanorods for MR imaging with low toxicity

Author affiliations

Abstract

We report the facile and scalable synthesis of a highly monodispersed inorganic nanostructure based on well-designed Gd(OH)3 nanorods. X-Ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), as well as energy-dispersive spectroscopy (EDS) were applied to characterize the samples, indicating that the nanomaterials with an average length of 100 nm and an average diameter of 15 nm showed a typical hexagonal phase. Biocompatibility tests were performed from in vitro cell experiments to in vivo long-term histological assessment, indicating that the Gd(OH)3 nanorods were promising for further bio-related application. Owing to the excellent paramagnetic behavior, we further investigated the capability of the nanorods as MRI contrast agent. Compared with the conventional Gd–DTPA complex, the well-designed Gd(OH)3 nanorods present a higher T1 relaxation rate, showing more potential for biomedicine applications.

Graphical abstract: Facile and large-scale synthesis of Gd(OH)3 nanorods for MR imaging with low toxicity

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 03 Dec 2011, accepted on 04 Mar 2012 and first published on 20 Mar 2012


Article type: Paper
DOI: 10.1039/C2NJ21009F
Citation: New J. Chem., 2012,36, 1335-1338
  •   Request permissions

    Facile and large-scale synthesis of Gd(OH)3 nanorods for MR imaging with low toxicity

    S. Huang, J. Liu, D. Liu and Q. Yuan, New J. Chem., 2012, 36, 1335
    DOI: 10.1039/C2NJ21009F

Search articles by author