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Issue 8, 2012
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Identification and molecular genetic analysis of the cichorine gene cluster in Aspergillus nidulans

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Abstract

We recently demonstrated that the phytotoxin cichorine is produced by Aspergillus nidulans. Through a set of targeted deletions, we have found a cluster of seven genes that are required for its biosynthesis. Two of the deletions yielded molecules that give information about the biosynthesis of this metabolite.

Graphical abstract: Identification and molecular genetic analysis of the cichorine gene cluster in Aspergillus nidulans

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Publication details

The article was received on 22 Feb 2012, accepted on 12 Apr 2012 and first published on 17 Apr 2012


Article type: Concise Article
DOI: 10.1039/C2MD20055D
Citation: Med. Chem. Commun., 2012,3, 997-1002
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    Identification and molecular genetic analysis of the cichorine gene cluster in Aspergillus nidulans

    J. F. Sanchez, R. Entwistle, D. Corcoran, B. R. Oakley and C. C. C. Wang, Med. Chem. Commun., 2012, 3, 997
    DOI: 10.1039/C2MD20055D

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