Broadening the field of opportunity for medicinal chemists. Official journal of the European Federation for Medicinal Chemistry
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Concise Article

Oxadiazole isomers: all bioisosteres are not created equal

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a
Cardiovascular and Gastrointestinal Innovative Medicines Unit, AstraZeneca, Mereside, Alderley Park, Macclesfield, Cheshire, UK
E-mail: Philip.MacFaul@astrazeneca.com ;
Tel: +44 (0)1625 516080
b
Medicines Evaluation CNSP, Pharm. Dev., AstraZeneca R&D Södertälje, 151 85 Södertälje, Sweden
c
School of Chemical Science and Engineering, Royal Institute of Technology, Teknikringen 30, 100 44 Stockholm, Sweden
d
Department of Chemistry, University of Huddersfield, Queensgate, Huddersfield West Yorkshire, UK
Med. Chem. Commun., 2012,3, 600-604

DOI: 10.1039/C2MD20054F
Received 22 Feb 2012, Accepted 15 Mar 2012
First published online 16 Mar 2012
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