Combining redox-proteomics and epigenomics to explain the involvement of oxidative stress in psychiatric disorders†
Abstract
Psychiatric disorders affect approximately 10% of adults in North-America. The complex nature of these illnesses makes the search for their pathophysiology a challenge. However, studies have consistently shown that mitochondrial dysfunction and oxidative stress are common features across major psychiatric disorders, including bipolar disorder and schizophrenia. Nevertheless, little is known about specific targets of
- This article is part of the themed collection: Molecular BioSystems Emerging Investigators 2012