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Issue 4, 2012
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High throughput production of single core double emulsions in a parallelized microfluidic device

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Abstract

Double emulsions are useful templates for microcapsules and complex particles, but no method yet exists for making double emulsions with both high uniformity and high throughput. We present a parallel numbering-up design for microfluidic double emulsion devices, which combines the excellent control of microfluidics with throughput suitable for mass production. We demonstrate the design with devices incorporating up to 15 dropmaker units in a two-dimensional or three-dimensional array, producing single-core double emulsion drops at rates over 1 kg day−1 and with diameter variation less than 6%. This design provides a route to integrating hundreds of dropmakers or more in a single chip, facilitating industrial-scale production rates of many tons per year.

Graphical abstract: High throughput production of single core double emulsions in a parallelized microfluidic device

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Publication details

The article was received on 25 Oct 2011, accepted on 19 Dec 2011 and first published on 06 Jan 2012


Article type: Paper
DOI: 10.1039/C2LC21033A
Citation: Lab Chip, 2012,12, 802-807
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    High throughput production of single core double emulsions in a parallelized microfluidic device

    M. B. Romanowsky, A. R. Abate, A. Rotem, C. Holtze and D. A. Weitz, Lab Chip, 2012, 12, 802
    DOI: 10.1039/C2LC21033A

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