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Issue 14, 2012
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Tunable patterning of microparticles and cells using standing surface acoustic waves

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Abstract

We have developed an acoustic-based tunable patterning technique by which microparticles or cells can be arranged into reconfigurable patterns in microfluidic channels. In our approach, we use pairs of slanted-finger interdigital transducers (SFITs) to generate a tunable standing surface acoustic wave field, which in turn patterns microparticles or cells in one- or two-dimensional arrays inside the microfluidic channels—all without the assistance of fluidic flow. By tuning the frequency of the input signal applied to the SFITs, we have shown that the cell pattern can be controlled with tunability of up to 72%. This acoustic-based tunable patterning technique has the advantages of wide tunability, non-invasiveness, and ease of integration to lab-on-a-chip systems, and shall be valuable in many biological and colloidal studies.

Graphical abstract: Tunable patterning of microparticles and cells using standing surface acoustic waves

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Publication details

The article was received on 20 Oct 2011, accepted on 03 Apr 2012 and first published on 31 May 2012


Article type: Paper
DOI: 10.1039/C2LC21021E
Citation: Lab Chip, 2012,12, 2491-2497
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    Tunable patterning of microparticles and cells using standing surface acoustic waves

    X. Ding, J. Shi, S. S. Lin, S. Yazdi, B. Kiraly and T. J. Huang, Lab Chip, 2012, 12, 2491
    DOI: 10.1039/C2LC21021E

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