Jump to main content
Jump to site search

Issue 5, 2012
Previous Article Next Article

Rapid, sensitive, and multiplexed on-chip optical sensors for micro-gas chromatography

Author affiliations

Abstract

We developed and characterized a rapid, sensitive and integrated optical vapor sensor array for micro-gas chromatography (μGC) applications. The sensor is based on the Fabry–Pérot (FP) interferometer formed by a micrometre-thin vapor-sensitive polymer layer coated on a silicon wafer. The thickness and the refractive index of the polymer vary in response to the vapor analyte, resulting in a change in the reflected intensity of the laser impinged on the sensor. In our study, four different polymers were coated on four wells pre-etched on a silicon wafer to form a spatially separated sensor array. A CMOS imager was employed to simultaneously monitor the polymers' response, thus enabling multiplexed detection of a vapor analyte passing through the GC column. A sub-second detection time was demonstrated. In addition, a sub-picogram detection limit was achieved, representing orders of magnitude improvement over the on-chip vapor sensors previously reported.

Graphical abstract: Rapid, sensitive, and multiplexed on-chip optical sensors for micro-gas chromatography

Back to tab navigation

Supplementary files

Publication details

The article was received on 24 Sep 2011, accepted on 22 Nov 2011 and first published on 16 Jan 2012


Article type: Paper
DOI: 10.1039/C2LC20922E
Citation: Lab Chip, 2012,12, 901-905
  •   Request permissions

    Rapid, sensitive, and multiplexed on-chip optical sensors for micro-gas chromatography

    K. Reddy, Y. Guo, J. Liu, W. Lee, M. K. Khaing Oo and X. Fan, Lab Chip, 2012, 12, 901
    DOI: 10.1039/C2LC20922E

Search articles by author

Spotlight

Advertisements