Department of Bioengineering and Therapeutic Sciences, California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, USA
Lab Chip, 2012,12, 4029-4032
19 Jun 2012,
16 Aug 2012
First published online
17 Aug 2012
Existing methods for injecting reagents into drops utilize metal electrodes integrated into the microfluidic chip, adding cumbersome and error-prone steps to the fabrication process. Here, we introduce a method that uses the injection fluid itself as an electrode by exploiting dissolved electrolytes in the solution. This obviates the need for metal electrodes and reduces fabrication time and complexity while also affording precise control of the injected reagent volumes.
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