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Issue 19, 2012
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Optical imaging techniques in microfluidics and their applications

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Microfluidic devices have undergone rapid development in recent years and provide a lab-on-a-chip solution for many biomedical and chemical applications. Optical imaging techniques are essential in microfluidics for observing and extracting information from biological or chemical samples. Traditionally, imaging in microfluidics is achieved by bench-top conventional microscopes or other bulky imaging systems. More recently, many novel compact microscopic techniques have been developed to provide a low-cost and portable solution. In this review, we provide an overview of optical imaging techniques used in microfluidics followed with their applications. We first discuss bulky imaging systems including microscopes and interferometer-based techniques, then we focus on compact imaging systems that can be better integrated with microfluidic devices, including digital in-line holography and scanning-based imaging techniques. The applications in biomedicine or chemistry are also discussed along with the specific imaging techniques.

Graphical abstract: Optical imaging techniques in microfluidics and their applications

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Publication details

The article was received on 06 May 2012, accepted on 28 Jun 2012 and first published on 04 Jul 2012

Article type: Critical Review
DOI: 10.1039/C2LC40517B
Citation: Lab Chip, 2012,12, 3566-3575
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    Optical imaging techniques in microfluidics and their applications

    J. Wu, G. Zheng and L. M. Lee, Lab Chip, 2012, 12, 3566
    DOI: 10.1039/C2LC40517B

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