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Issue 14, 2012
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Digital microfluidics: a versatile tool for applications in chemistry, biology and medicine

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Abstract

Digital microfluidics (DMF) has recently emerged as a popular technology for a wide range of applications. In DMF, nanoliter to microliter droplets containing samples and reagents can be manipulated to carry out a range of discrete fluidic operations simply by applying a series of electrical potentials to an array of patterned electrodes coated with a hydrophobic insulator. DMF is distinct from microchannel-based fluidics as it allows for precise control over multiple reagent phases (liquids and solids) in heterogeneous systems with no need for complex networks of connections, microvalves, or pumps. In this review, we discuss the most recent developments in this technology with particular attention to the potential benefits and outstanding challenges for applications in chemistry, biology, and medicine.

Graphical abstract: Digital microfluidics: a versatile tool for applications in chemistry, biology and medicine

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Publication details

The article was received on 03 Apr 2012, accepted on 04 May 2012 and first published on 10 May 2012


Article type: Critical Review
DOI: 10.1039/C2LC40318H
Citation: Lab Chip, 2012,12, 2452-2463
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    Digital microfluidics: a versatile tool for applications in chemistry, biology and medicine

    M. J. Jebrail, M. S. Bartsch and K. D. Patel, Lab Chip, 2012, 12, 2452
    DOI: 10.1039/C2LC40318H

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