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Issue 11, 2012
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Acoustofluidics 12: Biocompatibility and cell viability in microfluidic acoustic resonators

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Abstract

Manipulation of biological cells by acoustic radiation forces is often motivated by its improved biocompatibility relative to alternative available methods. On the other hand, it is well known that acoustic exposure is capable of causing damage to tissue or cells, primarily due to heating or cavitation effects. Therefore, it is important to define safety guidelines for the design and operation of the utilized devices. This tutorial discusses the biocompatibility of devices designed for acoustic manipulation of mammalian cells, and different methods for quantifying the cell viability in such devices.

Graphical abstract: Acoustofluidics 12: Biocompatibility and cell viability in microfluidic acoustic resonators

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Publication details

The article was received on 24 Feb 2012, accepted on 04 Apr 2012 and first published on 04 May 2012


Article type: Focus
DOI: 10.1039/C2LC40201G
Citation: Lab Chip, 2012,12, 2018-2028
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    Acoustofluidics 12: Biocompatibility and cell viability in microfluidic acoustic resonators

    M. Wiklund, Lab Chip, 2012, 12, 2018
    DOI: 10.1039/C2LC40201G

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