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Issue 4, 2012
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Droplet-based microfluidic device for multiple-droplet clustering

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Abstract

We present a multiple-droplet clustering device that can perform sequential droplet trapping and storing. Shape-dependent droplet manipulation in forward and backward flows has been incorporated to achieve high trapping and storing efficiency in a 10 × 12 array of clustering structures (e.g., storing well, storing chamber, trapping well, and guiding track). In the forward flow, flattened droplets are trapped in each trapping well. In the backward flow, the trapped droplets are released from the trapping well and follow the guiding tracks to their corresponding storing wells. The guided droplets float up out of the confining channel to the super stratum of the storing chamber due to interfacial energy and buoyancy effects. This forward/backward flow-based trapping/storing process can be repeated several times to cluster droplets with different contents and samples in the storing chambers. We expect that the proposed platform will be a valuable tool to study complex droplet-based reactions in clustered droplets.

Graphical abstract: Droplet-based microfluidic device for multiple-droplet clustering

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Publication details

The article was received on 14 Sep 2011, accepted on 22 Nov 2011 and first published on 13 Dec 2011


Article type: Paper
DOI: 10.1039/C2LC20883K
Citation: Lab Chip, 2012,12, 725-730
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    Droplet-based microfluidic device for multiple-droplet clustering

    J. Xu, B. Ahn, H. Lee, L. Xu, K. Lee, R. Panchapakesan and K. W. Oh, Lab Chip, 2012, 12, 725
    DOI: 10.1039/C2LC20883K

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