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Issue 6, 2012
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Gold nanorod assembly based approach to toxin detection by SERS

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Abstract

A novel, rapid and ultrasensitive surface-enhanced Raman scattering (SERS) immunoassay for the detection of microcystin LR was developed based on the assembly of gold nanorods (GNRs). GNRs were assembled into nanorod chains through the bio-recognition. The SERS signal of the probe molecule modified to the end of the NRs could be enhanced due to the hot spot between the NRs. Meanwhile, the finite integration technique simulation revealed that the electrical field of nanorods was increased obviously depending on the degree of end to end assembled structures. The research results demonstrated that the linear detection range was from 0.01 ng mL−1 to 5 ng mL−1, the limit of detection was 5 pg mL−1, and the time necessary for the analysis was only 15 min.

Graphical abstract: Gold nanorod assembly based approach to toxin detection by SERS

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Publication details

The article was received on 15 Oct 2011, accepted on 09 Dec 2011 and first published on 22 Dec 2011


Article type: Communication
DOI: 10.1039/C2JM15238J
Citation: J. Mater. Chem., 2012,22, 2387-2391
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    Gold nanorod assembly based approach to toxin detection by SERS

    Y. Zhu, H. Kuang, L. Xu, W. Ma, C. Peng, Y. Hua, L. Wang and C. Xu, J. Mater. Chem., 2012, 22, 2387
    DOI: 10.1039/C2JM15238J

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