Issue 12, 2012
From the journal:

Green Chemistry

Catalyst free approach to benzimidazoles using air as the oxidant at room temperature†

Chun Zhang,a   Liangren Zhanga  and  Ning Jiao*ab  

* Corresponding authors

a State Key Laboratory of Natural and Biomimetic Drugs, Peking University, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd. 38, Beijing 100191, China
E-mail: jiaoning@bjmu.edu.cn
Fax: (+86)-010-8280-5297
Tel: (+86)-010-8280-5297

b State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

Abstract

A green and practical method to construct benzimidazoles, which are ubiquitous structural units in a number of biologically active compounds, has been developed. The catalyst and additive free conditions, using air as oxidant and the mild conditions make this transformation very green, practical, and attractive.

Graphical abstract: Catalyst free approach to benzimidazoles using air as the oxidant at room temperature

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Article information

DOI
https://doi.org/10.1039/C2GC36416F
Article type
Communication
Submitted
06 Sep 2012
Accepted
08 Oct 2012
First published
09 Oct 2012

Green Chem., 2012,14, 3273-3276

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Catalyst free approach to benzimidazoles using air as the oxidant at room temperature

C. Zhang, L. Zhang and N. Jiao, Green Chem., 2012, 14, 3273 DOI: 10.1039/C2GC36416F

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