“On water” direct Pd-catalysed C–H arylation of thiazolo[5,4-d]pyrimidine derivatives†
Abstract
A novel protocol for the direct arylation of thiazolo[5,4-d]pyrimidine derivatives with aryl iodides is reported. The reactions were catalysed by a combination of Pd(PPh3)4 and Ag2CO3 (acting as the oxidant and the base as well), using exclusively