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Issue 45, 2012
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Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents

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Abstract

Several Ru-arene and Ir–Cp* complexes have been prepared incorporating (N,N), (N,O) and (O,O) coordinating bidentate ligands and have been found to be active against both HT-29 and MCF-7 cell lines. By incorporating a biologically active ligand into a metal complex the anti-cancer activity is increased.

Graphical abstract: Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents

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Publication details

The article was received on 13 Aug 2012, accepted on 13 Sep 2012 and first published on 14 Sep 2012


Article type: Communication
DOI: 10.1039/C2DT32104A
Citation: Dalton Trans., 2012,41, 13800-13802
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    Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents

    S. J. Lucas, R. M. Lord, R. L. Wilson, R. M. Phillips, V. Sridharan and P. C. McGowan, Dalton Trans., 2012, 41, 13800
    DOI: 10.1039/C2DT32104A

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