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Department of Basic Medical Sciences, Royal College of Surgeons in Ireland Medical University of Bahrain, Building No. 2441, Road 2835, Busaiteen 228, PO Box 15503, Adliya, Kingdom of Bahrain
; Tel: +973-17-351450-2300
Centre for Synthesis & Chemical Biology, Department of Pharmaceutical & Medicinal Chemistry, Royal College of Surgeons in Ireland, 123 St. Stephens Green, Dublin 2, Ireland
; Fax: +353 1 402 2168
; Tel: +353 1 402 2246
Dalton Trans., 2012,41, 13239-13257
18 Jul 2012,
17 Aug 2012
First published online
20 Aug 2012
Metal complexes and metal salts have a wide range of medicinal applications and are extensively administered to patients or purchased over the counter as a matter of routine. The abundance and variety of non-platinum metal complexes, which are approved for use as therapeutic or diagnostic agents, are highlighted. Current insights into the mechanism of action or indeed lack thereof of a selection of metallodrugs are discussed. Ultimately this perspective seeks to inspire chemists to tackle new challenges and raise awareness of opportunities in the area of inorganic therapeutic and diagnostic medicine.
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