Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 46, 2012
Previous Article Next Article

Selective synthesis of 6,8-di-t-butylated flavan over Zn–Al containing mesoporous silica catalysts

Author affiliations

Abstract

We demonstrate a much green synthesis method for highly selective synthesis of 6,8-di-t-butylated flavan (6,8-DTBF) by liquid phase alkylation of 2,4-di-t-butylphenol (2,4-DTBP) with cinnamyl alcohol (Cin-OH) over mesoporous Zn–Al–MCM-41 catalysts synthesized under direct basic hydrothermal method. The main alkylated product, 6,8-DTBF is importantly used as an intermediate in the manufacture of biosynthetic organic compounds. The recyclable mesoporous Zn–Al–MCM-41 catalysts have also been reused in this reaction to study their catalytic activities. The influences of various reaction parameters such as temperature, time, ratios of reactant (2,4-DTBP-to-Cin-OH) have been extensively investigated for the synthesis of 6,8-DTBF. In addition, dimethyl sulfoxide (DMSO) has also been used as a solvent in this catalytic reaction. The mesoporous Zn–Al–MCM-41(75) gives excellent catalytic activity with 6,8-DTBF selectivity (86.0%) and 2,4-DTBP conversion (63.1%), and these catalytic results have also compared with that obtained using other mesoporous and microporous catalysts. On the basis of catalytic activity obtained by using the all catalysts, the Zn–Al–MCM-41(75) catalyst is found to be a highly active, recyclable and eco-friendly heterogeneous catalyst in the liquid-phase alkylation of 2,4-DTBP.

Graphical abstract: Selective synthesis of 6,8-di-t-butylated flavan over Zn–Al containing mesoporous silica catalysts

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 29 Jun 2012, accepted on 28 Aug 2012 and first published on 09 Oct 2012


Article type: Paper
DOI: 10.1039/C2DT31409F
Citation: Dalton Trans., 2012,41, 14197-14203
  •   Request permissions

    Selective synthesis of 6,8-di-t-butylated flavan over Zn–Al containing mesoporous silica catalysts

    M. Selvaraj, P. K. Sinha, D.-W. Park, I. Kim, S. Kawi and C. S. Ha, Dalton Trans., 2012, 41, 14197
    DOI: 10.1039/C2DT31409F

Search articles by author