Jump to main content
Jump to site search

Issue 6, 2012
Previous Article Next Article

Gold nanoparticles in biomedical applications: recent advances and perspectives

Author affiliations

Abstract

Gold nanoparticles (GNPs) with controlled geometrical, optical, and surface chemical properties are the subject of intensive studies and applications in biology and medicine. To date, the ever increasing diversity of published examples has included genomics and biosensorics, immunoassays and clinical chemistry, photothermolysis of cancer cells and tumors, targeted delivery of drugs and antigens, and optical bioimaging of cells and tissues with state-of-the-art nanophotonic detection systems. This critical review is focused on the application of GNP conjugates to biomedical diagnostics and analytics, photothermal and photodynamic therapies, and delivery of target molecules. Distinct from other published reviews, we present a summary of the immunological properties of GNPs. For each of the above topics, the basic principles, recent advances, and current challenges are discussed (508 references).

Graphical abstract: Gold nanoparticles in biomedical applications: recent advances and perspectives

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 19 Jun 2011 and first published on 30 Nov 2011


Article type: Critical Review
DOI: 10.1039/C1CS15166E
Citation: Chem. Soc. Rev., 2012,41, 2256-2282
  •   Request permissions

    Gold nanoparticles in biomedical applications: recent advances and perspectives

    L. Dykman and N. Khlebtsov, Chem. Soc. Rev., 2012, 41, 2256
    DOI: 10.1039/C1CS15166E

Search articles by author