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Issue 26, 2012
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Exploring the thermodynamic derivatives of the structure factor of dense protein solutions

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Abstract

Using small-angle X-ray scattering data of concentrated solutions of the protein lysozyme taken at different pressures and temperatures, the isothermal pressure derivative and the isobaric temperature derivative of the structure factor S(q) were determined. The pressure derivative of S(q) allows us to test various models for the triplet correlation function g3. Significant differences were found in comparison to simple liquids reflecting the more complex interaction potential in dense protein solutions.

Graphical abstract: Exploring the thermodynamic derivatives of the structure factor of dense protein solutions

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Publication details

The article was received on 09 Mar 2012, accepted on 02 May 2012 and first published on 02 May 2012


Article type: Paper
DOI: 10.1039/C2CP41041A
Citation: Phys. Chem. Chem. Phys., 2012,14, 9486-9491
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    Exploring the thermodynamic derivatives of the structure factor of dense protein solutions

    M. A. Schroer, M. Tolan and R. Winter, Phys. Chem. Chem. Phys., 2012, 14, 9486
    DOI: 10.1039/C2CP41041A

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