Cascade imaging of proteolytic pathways in cancer cells using fluorescent protein-conjugated gold nanoquenchers

Kyoungsook Park; Jinyoung Jeong; Bong Hyun Chung

doi:10.1039/C2CC35687B

Cascade imaging of proteolytic pathways in cancer cells using fluorescent protein-conjugated gold nanoquenchers

Kyoungsook Park,^a Jinyoung Jeong^a and Bong Hyun Chung*^a

* Corresponding authors

^a BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Major of Nanobiotechnology, University of Science and Technology, Gwahangno, Yuseong, Republic of Korea
E-mail: chungbh@kribb.re.kr
Fax: +82 42 879 8594
Tel: +82 42 860 4442

Abstract

The real-time monitoring of the caspase cascade in cancer cells during apoptosis was performed using various caspase substrate-linked fluorescent proteins-conjugated gold nanoparticles as a new imaging probe.

Supplementary files

Publication details

The article was received on 06 Aug 2012, accepted on 07 Sep 2012 and first published on 10 Sep 2012

Article type: Communication

DOI: 10.1039/C2CC35687B

Citation: Chem. Commun., 2012,48, 10547-10549

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Cascade imaging of proteolytic pathways in cancer cells using fluorescent protein-conjugated gold nanoquenchers

K. Park, J. Jeong and B. H. Chung, Chem. Commun., 2012, 48, 10547
DOI: 10.1039/C2CC35687B
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Chemical Communications

Cascade imaging of proteolytic pathways in cancer cells using fluorescent protein-conjugated gold nanoquenchers

Abstract

Supplementary files

Publication details

Cascade imaging of proteolytic pathways in cancer cells using fluorescent protein-conjugated gold nanoquenchers

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