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Issue 86, 2012
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A selective fluorescent probe for thiols based on α,β-unsaturated acyl sulfonamide

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Abstract

We report herein a novel fluorescent probe based on α,β-unsaturated acyl sulfonamide to detect thiols. The probe has good water solubility and reacts with thiols under aqueous conditions. It reacts selectively with cysteine but not with the other natural amino acids. The probe was subsequently applied to detect intracellular thiols.

Graphical abstract: A selective fluorescent probe for thiols based on α,β-unsaturated acyl sulfonamide

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Publication details

The article was received on 08 Jun 2012, accepted on 07 Sep 2012 and first published on 11 Sep 2012


Article type: Communication
DOI: 10.1039/C2CC35513B
Citation: Chem. Commun., 2012,48, 10672-10674
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    A selective fluorescent probe for thiols based on α,β-unsaturated acyl sulfonamide

    H. Zhang, P. Wang, Y. Yang and H. Sun, Chem. Commun., 2012, 48, 10672
    DOI: 10.1039/C2CC35513B

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