nBu4NI-catalyzed direct synthesis of α-ketoamides from aryl methyl ketones with dialkylformamides in water using TBHP as oxidant

Wen-Peng Mai; Hui-Hui Wang; Zhi-Cheng Li; Jin-Wei Yuan; Yong-Mei Xiao; Liang-Ru Yang; Pu Mao; Ling-Bo Qu

doi:10.1039/C2CC35279F

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

nBu₄NI-catalyzed direct synthesis of α-ketoamides from aryl methyl ketones with dialkylformamides in water using TBHP as oxidant†

Wen-Peng Mai,*^a Hui-Hui Wang,^a Zhi-Cheng Li,^a Jin-Wei Yuan,^a Yong-Mei Xiao,^a Liang-Ru Yang,^a Pu Mao^a and Ling-Bo Qu*^a

Author affiliations

* Corresponding authors

^a School of Chemistry and Chemical Engineering, Henan University of Technology, Lianhua Street, Zhengzhou, 450001, P. R. China
E-mail: maiwp@yahoo.com, qulingbo@haut.edu.cn
Fax: +86-371-67756715
Tel: +86-371-67756718

Abstract

A novel and easy practical direct synthesis of α-ketoamides has been developed without metals in water. This procedure was catalyzed by nBu₄NI using TBHP as oxidant from simple substrates, aryl methyl ketones and dialkylformamides.

Download options Please wait...

Supplementary files

Supplementary information PDF (2963K)

Article information

DOI: https://doi.org/10.1039/C2CC35279F
Article type: Communication
Submitted: 22 Jul 2012
Accepted: 22 Aug 2012
First published: 23 Aug 2012

Download Citation

Chem. Commun., 2012,48, 10117-10119

Permissions

Request permissions

nBu₄NI-catalyzed direct synthesis of α-ketoamides from aryl methyl ketones with dialkylformamides in water using TBHP as oxidant

W. Mai, H. Wang, Z. Li, J. Yuan, Y. Xiao, L. Yang, P. Mao and L. Qu, Chem. Commun., 2012, 48, 10117 DOI: 10.1039/C2CC35279F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications